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Selective Androgen Receptor Modulators (SARMs) are a class of therapeutic compounds that have similar properties to anabolic agents, but with reduced androgenic properties. This property allows SARMs the advantage of androgen-receptor specificity, tissue selectivity, and the lack of steroid-related side effects.
SARMs or Selective Androgen Receptor Modulators contain androgens which are a special kind of hormones that act as ligands connecting to cellular androgen receptors. The androgen receptors (AR) integrated in a composite signal transduction conduit that ultimately leads to bigger expression of particular genes. This connection to the AR is what makes all prohormones and steroids give their muscle growth properties.
Selective Androgen Receptor Modulators (SARMs) are currently being developed as an alternative to prescribed steroids. SARMs are able to selectively cause muscle growth, while reducing or eliminating unwanted secondary side effects. The problems with anabolic steroids or testosterone replacement therapy are undesirable side effects that occur.
Steroids have typically been prescribed in medicine for two distinct reasons:
- Muscle wasting diseases ranging from cancer to osteoporosis
- Hormone replacement therapy
- Increase in fat loss
- Increase in lean muscle
- Improvements in endurance
- Increase in bone density
- Faster recovery periods
- Healing properties
- Increase in muscle mass and size
- Strength increases
Ostarine (best SARM overall)
Ostarine (MK-2866), also known as enobosarm, is one of the most researched sarms on the market. Its powerful anabolic effects, fat loss effects and joint healing properties make it the most popular sarm. Ostarine is commonly used for bulking, fat loss and body recomp. It is recommended for beginners.
Andarine S4 (best choice for women)
Research has shown that S4 SARM , Andarine S4, binds to the androgen receptor which creates an increase in the expression of genes associated in protein synthesis which would in turn increase lean muscle mass. Studies have shown S-4 preserves lean muscle mass as well as increasing it making it a great benefit to fighting osteoporosis and muscle degeneration. S-4 is known to be one of the most popular SARMS because research has shown the potential for increased stamina, lean muscle mass, and vascularity.
Andro Max LGD-4033 (great for bulking)
Ligandrol (LGD 4033), also known as anabolicum, is the most anabolic sarm on the market. It is popular for its powerful effects on muscle growth, strength improvement, and putting on size. It is best used in bulking cycles. Stack Ligandrol with RAD 140 for incredible muscle growth!
Testolone (RAD 140) stimulates androgen receptors in the bones and muscles with greater affinity than in the reproductive organs. Studies have shown that RAD 140 can increase muscle mass, decrease fat, and improve cardiovascular performance. RAD 140 is best used for bulking and for body recomp. RAD 140 is quite well-rounded in that it offers benefits that match all goals (muscle gain, fat loss, endurance & body recomp).
Myo Booster YK-11 (the strongest SARM)
Research has shown that YK-11 is very anabolic and androgenic. Research has shown YK-11 binds to the androgen receptor in muscles and produces drastic increases in muscle. Research has shown YK-11 also inhibits follistatin which in turn inhibits myostatin which is a protein that limits the growth of muscular tissues therefore while present the chemical can actually alter genetic potential to build muscle tissue. Because of selectivity of YK-11 research has shown strong anabolic effects in building muscle at a rapid speed but also it doesn’t act on androgen receptors on other parts of the body.
Cardarine GW-501516 is most commonly used for its powerful fat loss effects and its cardiovascular endurance benefits. Cardarine is best used in cutting cycles and for body recomp.
GW-501516 (Cardarine) is a compound that activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue. Studies have shown GW-501516 to reverse metabolic abnormalities in obese men and has been proposed as a potential treatment for obesity. GW-501516 is also known as Cardarine and it has been shown to increase endurance in animal studies.
LGD-4033 ( Ligandrol ) is a SARM expected to produce therapeutic benefits of testosterone with improved safety due to its tissue selective nature. LGD-4033 has androgen receptor ligands that are tissue selective and was developed to treat muscle wasting and age-related muscle loss. LGD-4033 is also known as Ligandrol and was developed to fight muscle wasting associated with cancer and acute and chronic illness.
Also known as Nutrobal, MK-677 has been shown in two clinical studies to significantly increase human growth hormone production, leading mainly to muscle growth, improving sleep quality and recovery. Ibutamoren is best used for bulking and for body recomp. Recommended to stack it with LGD-4033, Ostarine, RAD 140.
Is one of the best Sarms for cutting. Enhance cardiovascular performance and increase your metabolism. Commonly stacked with our cutting cycle for increased fat loss.
Research has shown SR-9009 stenabolic, stimulates the Rev-Erb protein which has an effect on circadian rhythms, fat-storing cells as well as glucose and lipid metabolism. Research has shown that activating Rev-erb protein increases cell production through mitochondria giving the muscle increased energy as well as giving the metabolism enhanced speed. Thus increasing the mitochondria in the muscle will result in strength gain as well as drastic energy increase to go along with strides in endurance. Research has shown Stenabolic can can increase all around endurance due to increases in mitochondria count. The biggest component that SR-9009 research shows is that it boosts metabolic activity and is known to mimic aerobic exercise without having to actually exercise hence being called “exercise in a bottle”. Research shows SR9009 uses body fat that is stored and uses it as energy for exercise.
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