SARMs were created around the 1940s after researchers modified the chemical structure of the testosterone molecule.
These early SARMs differ a lot from the SARMs that exist nowadays since the first ones were created from a testosterone molecule and those that are being created nowadays do not have a steroidal origin, therefore it does not make sense to compare them with conventional steroids since they do not come from the same origin.
SARM stands for Selective androgen receptor modulator (For example, trenbolone at low doses could be considered a SARM) or to better understand it, just as SERMs, such as tamoxifen, exert their action on estrogen receptors, SARMs will exert it on androgen receptors
SARMs were created with the idea of obtaining a compound with zero or almost zero androgenic activity (so as not to affect the prostate and even help with prostate problems) and with high anabolic activity in skeletal muscle tissue through a direct relationship with.
Therefore we have substances with a high anabolic activity, a low or no androgenic and estrogenic response and that cause a much lower liver stress ...Sounds perfect, right?
The main problem that we can find nowadays is that there are not many human clinical trials on SARMs published, the doses used in studies are much lower than those used by the average user of PEDs (and despite being low they give very good results in studies) and the rest of tests are carried out in animals, usually rats in which the anabolic effect is measured by seeing the growth of a muscle of the pelvis / anus ...
Therefore the opinions expressed here will be based mainly on studies carried out in humans and the results obtained for me, my athletes and the experiences of various users in forums.
When it binds with androgen receptors, the testosterone hormone helps the body to grow facial hair, gain muscle, lose body fat, deepen your voice, etc. The androgen receptors then transform into Dihydrotestosterone (DHT), which converts into estrogen, and binds with the receptors in the cell.
This process continues naturally until old age when the body stops producing as much testosterone. SARMs stimulate the cells to produce androgens so that the muscles can continue to grow.
The drugs worked miracles for elderly people and cancer patients who were dealing with chronic fatigue, osteoporosis, and anemia. Scientists claim that SARMs can help treat obesity, boost appetite, improve bone health, and prevent muscle wastage.
This section will talk about the different types of SARMs.
The most popular SARM is Ostarine. It helps to preserve the muscle you have gained at the gym. It can do this even when you’re on a caloric deficit. On average, you should take 10 to 25 mg of this drug for six to ten weeks.
Ostarine reduces the production of testosterone when used for a long period of time, so you also have to consume SERM PCT. The supplement is known to cause Gynecomastia in some people; hence, having an Aromatase Inhibitors (AI), such as Exemestane is important.
RAD140 Testolone has an anabolic to androgenic ratio of 90:1, which means that users can gain muscle, lose weight, heal skeletal problems, feel stronger, and reduce muscle waste without any side effects.
This supplement needs to be taken twice a day, with doses ranging between 4 to 12 mg for four to six weeks. It also minimizes the effect of testosterone on the prostate, so you must take a Post Cycle Therapy (PCT) at the end of the cycle.
GW501516 is more like a PPAR Delta Modulator that regulates the metabolism and development of cells. It creates more muscle tissue by using more glucose.
The dosage should be as low as 7 mg, and no higher than 20 mg. This is a non-hormonal supplement, so it won’t affect your testosterone levels.
It also makes you more energetic, improves muscle mass, and increases endurance. Some people believe that Cardarine GW501516 improves the lipid profile and blood pressure.
MK 677 is a non-peptide and a secretion-boosting receptor. It promotes IGF-1 levels and the growth hormone by copying the functions of ghrelin. Luckily, it won’t affect your cortisol level.
This supplement has shown that IGF-1 levels can be increased by 60% in just six months, whereas IGF-1 levels can be increased by 72% in 12 months. You should use it for about six months, increasing the dosage every month.
It’s non-hormonal, so you won’t be needing a PCT at the end of the cycle. Tingly hands and feeling numb are the common side effects of MK677, so be aware.
LGD4033 Ligandrol is like Ostarine, but more powerful. It suppresses the Hypothalamus-Pituitary-Testes-Axis system; hence, you need to undergo Selective Estrogen Receptor Modulator (SERM) therapy after the completion of the cycle.
Anabolic delivers great benefits such as boosting muscle growth, increasing anabolic activity and energy production, no steroid side effects, injections not included. In terms of supplements, there are many different choices available
Andarine S4 can build muscles very quickly. The dosage is lower than those used in previous SARMs.
However, it’s known to alter vision in users who have been consuming it at 50 mg. Therefore, sticking to a minimum dosage of 10 mg is recommended. At the end of the cycle, you will need PCT.
The effects of SR9009 Stenabolic are intracellular level, which means you can experience a fantastic impact in terms of amplified metabolism.
Helps With Weight Loss – SR9009 helps to keep the resting metabolism high, which is a great platform for weight loss. It will build muscle mass through driving the amino acids compounds from your bloodstream into your muscle tissue. Muscle tissue is metabolically active than fat, so by increasing muscle mass, you will be naturally boosting your metabolism.